Lou Gehrig’s Disease Linked to Low Glutathione Levels
Although treatment for ALS, Lou Gehrig’s disease has still eluded those in the medical profession, scientists have discovered mechanisms that are underlying the disease process that are considered to be useful in the clinical management of ALS, giving new hope for significantly slowing the disease process and improving the quality of life for these patients.
The following article published in PubMed makes it very clear as to the possible benefits that increasing glutathione will have on slowing the progression of the disease. Although, this is not a “cure” it is certainly a step in the right direction in treating a disease that up until now has only one outcome.
A study of glutathione S-transferase pi expression in central nervous system of subjects with amyotrophic lateral sclerosis using RNA extraction from formalin-fixed, paraffin-embedded material.
Usarek E, Gajewska B, Ka?mierczak B, Ku?ma M, Dziewulska D, Bara?czyk-Ku?ma A.
Department of Biochemistry, Medical University of Warsaw, Banacha 1, 02-097, Warsaw, Poland.
The expression of glutathione S-transferase pi (GST pi), an enzyme responsible for inactivation of a large variety of toxic compounds was studied in spinal cord, motor and sensory brain cortex obtained from patients who died in the course of amyotrophic lateral sclerosis (ALS). The studies were performed on formalin-fixed, paraffin-embedded (FFPE) and freshly frozen tissues. The method of RNA isolation from FFPE was modified. A significant decrease of GST pi-mRNA expression was found in cervical spinal cord and motor brain cortex of ALS subjects comparing to analogue control tissues (P<0.01), as well as in motor cortex of ALS subjects comparing to their sensory cortex (P<0.05). In spinal cords the decrease in GST pi-mRNA expression was accompanied by a decrease of GST pi protein level. Results indicated lowered GST pi expression on both mRNA and protein levels in the regions of nervous system affected by ALS. The non-properly inactivated by GST toxic electrophiles and organic peroxides may thus contribute to motor neurons damage.
Glutathione’s role is to protect us against the main villains (toxins) that are at the root of aging and the multitude of diseases that are commonplace in society today. Glutathione in essence is the body’s Master Antioxidant! Yes, we have our own detoxification system built right in from birth.
Glutathione is rapidly consumed on a daily basis through normal metabolism, exercise and illnesses. We regenerate glutathione repeatedly but unfortunately more is lost than is manufactured by the body. We lose approximately 8 -12% of glutathione levels per decade from age 20 on. It is no wonder that the aging process seems to hit so many by their 40’s.
Without your glutathione levels at a optimum level, you have less than adequate defenses against may illnesses and diseases, including diabetes, heart disease, hypertension, lupus, Lou Gehrig’s disease and the list goes on.
How to Raise Your Glutathione Levels
Glutathione is made by the cells in our bodies from 3 amino acids: glycine, glutamate and cysteine. Cysteine is the most important part of this equation and the most difficult to get.
Research Scientist, Dr. Robert Keller, MD, MS, FACP, AAHIVS, the Director of Medicine and Research/KBK at the Institute of Advanced Medicine, has spent years on developing a way to help the body to produce glutathione to increase the quality of life for many of his patients. His research has lead to the revolutionary product that is a formulation of natural ingredients that is proven to increase the levels of glutathione in the body by 400%.
With Dr. Keller’s research and the many positive results that he has seen in the quality of life for his patients, he could see the potential for everyone taking this product to have a better quality of life, regardless of illness or age.
To find out more about Dr. Keller’s revolutionary product go to: MaxGXL Glutathione Accelerator
